Mitopure®, the nutrient that can re‑energize cells
As we age, our cells age. Mitopure® is the first postbiotic nutrient shown to trigger a crucial recycling process within our cells called mitophagy, targeting age-related cellular decline*.
~90% of our cellular energy is produced by mitochondria
Mitochondria are our cellular powerhouses. The trillions of cells that comprise our body tissues run on the energy created by them.
Mitochondria are the bedrock of good health
Healthy cells rely on healthy mitochondria. Their optimal function leads to incredible health benefits, and is particularly essential to heart, kidney, eye, brain, skin and muscle function. Our clinical science to date has focused on muscle health as muscle cells have a very large number of mitochondria and on skin health, as the largest organ in our body.
Digestive system
The digestive system is essential to human well-being. Mitochondrial health has been associated with improved gut barrier health, a reduced risk of fatty liver disease, improved kidney function and lower risk of glucose intolerance.
Brain
The human brain uses about 25% of the human body’s metabolic energy and is particularly sensitive to the aging process. A growing number of scientists are looking into the contributions of mitochondria in brain health with preliminary studies suggesting they could be key players in brain disorders.
Immune system
The immune system protects us from infections and from excessive inflammation. With age, its control loosens up. Evidence is rising on the importance of mitochondria to reduce inflammation with aging, also known as inflamm-aging.
Heart
A 2018 report reviewed recent evidence implicating mitochondrial dysfunction in the development of heart failure. “Oxidative metabolism in mitochondria is the main energy source of the heart, and the inability to generate and transfer energy has long been considered the primary mechanism linking mitochondrial dysfunction and contractile failure.”
Joints
Joints are key for our mobility. The cells required to keep our joints functional progressively decline in function, and so do their mitochondria. These powerhouses need to be renewed and nourished to keep our joints healthy. There is emerging science around the link between mitochondria and arthritis.
Skeletal muscle
During strenuous exercise, the rate of energy use in skeletal muscles can increase by more than 100-fold almost instantly. To meet this energy demand, muscle cells contain mitochondria. Our clinical studies have shown improved muscle strength and endurance as a result of improved mitochondrial function.
Skin
Skin, our largest organ and interface with the world, requires a lot of energy to combat aging, which mitochondria provide. As we age, dysfunctional mitochondria lead to reduced energy production, cellular decline, and skin signs of aging like sagginess, dullness, wrinkles, and weakened skin barrier. This can impact our overall health. Our clinical studies reveal enhanced mitochondrial function, improving skin cellular energy, youthfulness, resilience, and overall health.
Digestive system
The digestive system is essential to human well-being. Mitochondrial health has been associated with improved gut barrier health, a reduced risk of fatty liver disease, improved kidney function and lower risk of glucose intolerance.
Brain
The human brain uses about 25% of the human body’s metabolic energy and is particularly sensitive to the aging process. A growing number of scientists are looking into the contributions of mitochondria in brain health with preliminary studies suggesting they could be key players in brain disorders.
Immune system
The immune system protects us from infections and from excessive inflammation. With age, its control loosens up. Evidence is rising on the importance of mitochondria to reduce inflammation with aging, also known as inflamm-aging.
Heart
A 2018 report reviewed recent evidence implicating mitochondrial dysfunction in the development of heart failure. “Oxidative metabolism in mitochondria is the main energy source of the heart, and the inability to generate and transfer energy has long been considered the primary mechanism linking mitochondrial dysfunction and contractile failure.”
Joints
Joints are key for our mobility. The cells required to keep our joints functional progressively decline in function, and so do their mitochondria. These powerhouses need to be renewed and nourished to keep our joints healthy. There is emerging science around the link between mitochondria and arthritis.
Skeletal muscle
During strenuous exercise, the rate of energy use in skeletal muscles can increase by more than 100-fold almost instantly. To meet this energy demand, muscle cells contain mitochondria. Our clinical studies have shown improved muscle strength and endurance as a result of improved mitochondrial function.
Skin
Skin, our largest organ and interface with the world, requires a lot of energy to combat aging, which mitochondria provide. As we age, dysfunctional mitochondria lead to reduced energy production, cellular decline, and skin signs of aging like sagginess, dullness, wrinkles, and weakened skin barrier. This can impact our overall health. Our clinical studies reveal enhanced mitochondrial function, improving skin cellular energy, youthfulness, resilience, and overall health.
As we age, mitochondrial function declines
Our mitochondria are constantly renewed to produce energy and fulfill the vast energy demands of muscle, skin and other tissues. As we get older, mitochondrial renewal declines and dysfunctional mitochondria accumulate in the cells, resulting in significant issues.
Insufficient energy supply
Production of harmful molecules
Reduced cellular health
This decline starts earlier than you might think
Age-associated mitochondrial decline leads to a progressive decline in our metabolism, our overall energy levels, our resiliency, our skin health and our muscle function.
Healthy aging
Average aging
Muscle function
Age
Healthy cells rely on a powerful recycling process
A process called mitophagy cleans up defective mitochondria and allows the mitochondria to repair themselves and improve their performance. This recycling and cleansing mechanism is proven to provide valuable health benefits.
Better mitochondria quality
Improved cellular health
Improved muscle strength
Improved skin health
Meet Urolithin A, a rare molecule that renews our cellular powerhouses
Our scientists unlocked the power of Urolithin A, a molecule that stimulates this crucial recycling and cleansing process - ultimately protecting cells from age-associated decline.
Mitopure® is a highly pure form of Urolithin A
Scientists and physicians are thoroughly studying the impact of Mitopure® on human health and the results are impressive. By energizing cells, Mitopure® is revolutionizing cellular aging.
Energy
Strength
Endurance
Optimal Levels
Energy
Youthfulness
Resilience
Gentle power
All made possible by a team of leading scientists
We are supported by the knowledge and guidance of an accomplished group of scientific and clinical advisors with expertise spanning microbiome science, genomics, metabolomics, gastroenterology, immunology, nutrition, dermatology and human clinical research.
Dr. Johan Auwerx MD, PhD
Scientific Advisor
Professor. Johan Auwerx directs the Laboratory for Integrated and Systems Physiology at École Polytechnique Fédérale (EPFL) in Lausanne, Switzerland, where he studies the mechanisms that control how metabolisms are controlled and the factors that make them more or less effective. Focusing on longevity, his team is using multiple animal species to test a specific compound, Urolithin A, which could potentially restore much-needed muscle strength and energy to people as they age. Prof. Auwerx is a scientific advisor to Amazentis.
Dr. Patrick Aebischer, MD
Chairman, Scientific Advisory Board
Professor Patrick Aebischer, chairman and co-founder of Amazentis, is a medical doctor, neuroscientist and longtime researcher. He has held distinguished positions in his home country of Switzerland, as President of the École Polytechnique Fédérale de Lausanne (EPFL) and in the United States at Brown University in Providence.
Dr. Carmen Sandi, PhD
Scientific Advisor
Director, Brain and Mind Institute and Professor at the EPFL, Lausanne, Switzerland | Neurobehavioral science and stress related brain disorders
Dr. Navindra Seeram, PhD
Scientific Advisor
Navindra P. Seeram, Ph.D, Professor in the College of Pharmacy at the University of Rhode Island. He is an expert in plants and products derived from them that can be used for medicinal purposes in humans. Navindra Seeram is a scientific advisor to Amazentis.
Dr. Michel Aguet, MD
Scientific Advisor
Professor Emeritus, EPFL, Lausanne Switzerland, Former Director of the Swiss Institute for Experimental Cancer Research (ISREC) | Cancer biology, molecular biology, stem cells and drug target validation
Eric Verdin, MD
CEO Buck Institute for Research on Aging, Scientific Advisor
Dr. Eric M. Verdin, is a leading authority on aging research and metabolic science, has been at the helm of the Buck Institute for Research on Aging as its President and CEO since 2016. Specializing in the intricate relationship between diet, molecular biology, and age-related diseases, Dr. Verdin has contributed extensively to the field with over 210 scholarly articles and a portfolio of 15+ patents. As a professor and researcher, his work delves into understanding the proteins and molecules that influence the aging process and associated health conditions.
Roger Fielding, PhD
Clinical Advisor
Director and Senior Scientist of Nutrition, Exercise Physiology and Sarcopenia Laboratory, Tufts University | Exercise physiology, nutrition, sarcopenia
Jeremy D. Walston, MD
Clinical Advisor
The Raymond and Anna Lublin Professor of Geriatric Medicine and Gerontology Principal Investigator, Johns Hopkins Older Americans Independence Center Co-Director, Biology of Healthy Aging Program Johns Hopkins University School of Medicine | Geriatric medicine, chronic inflammation and mitochondrial biology, frailty research
Knowledge is power
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